徐宏喜教授，现为上海中医药大学教授、博士生导师、上海中医药大学中药学院院长。特聘教授，特聘专家。1994年获得日本富山医科药科大学国立和汉药研究所药学博士学位。并于新加坡国立大学化学系及加拿大Dalhousie大学微生物学系进行博士後研究工作。曾先后受聘于香港中文大学中药研究中心科学主任、香港和记黄埔(中国)有限公司副总经理兼高级医药顾问，上海和黄药业有限公司董事兼研究开发总监。2001至2010年,担任香港赛马会中药研究院副总裁兼中药研究室主任。徐教授至今已发表SCI论文200多篇。总引用次数超过5500次，H指数为40，入选2014年中国高被引用学者榜。拥有1项PCT专利以及6项美国专利。
徐教授的主要社会兼职包括：中华中医药学会中药实验药理学分会主任委员、世界中医药协会联合会中药分析专业委员会副会长、世中联中药鉴定专业委员会副会长、全国中医药高等教育学会中药教育研究会第三届理事会副理事长、国际现代化中医药学术会议联席主席、上海市侨界知识分子联谊会第八届理事会常务理事、上海市药学会中药专业委员会主任委员、国际国内十余种学术刊物的编委、现代化中医药国际协会创会董事等职。先后应邀前往美国、日本、新加坡、韩国、巴西、加拿大、奥地利、印度等国家以及台湾、香港、澳门等地做特邀学术报告或学术大会报告。
主要研究领域包括中药活性成分及药效评价研究，中药新药开发以及中药质量控制分析方法研究等。重点进行病毒、肿瘤、耐药菌及糖尿病等重大疾病的中药防治与药效评价研究，阐明中药药效物质基础及作用机制，研发具有自主知识产权的创新药物。
抗病毒及抗耐药菌中药药理机制研究:从事中药及其活性成分抗病毒及抗耐药菌药理作用机制研究。已建立抗病毒（HSV和EV71）筛选平台及基于MgrA靶标蛋白荧光探针的高通量筛选体系，致力于阐明中药抗病毒和抗金黄色葡萄球菌耐药菌活性物质基础，揭示其药效作用机制，发现活性强、毒性小、选择性高的先导化合物。
抗肿瘤中药药理作用机制研究:从事中药及其活性成分抗肿瘤药理作用机制研究。已建立分子、细胞及动物水平的抗肿瘤药物筛选及药效评价模型，重点开展肝癌、前列腺癌及胰腺癌的体内外药效筛选和药效评价，致力于从中草药和天然产物中寻找抗肿瘤先导化合物，阐明其诱导肿瘤细胞凋亡、调节自噬、抑制转移及防止复发等药效作用机制。近年来重点开展中国产藤黄属植物中具有抗肿瘤活性的PPAPs类和xanthones类成分的鉴定及其作用机制研究。
主要SCI研究论文（IF》3）
1. Y. Z. Lao, G. Wan, Z. Y. Liu, X. Y. Wang, P. Ruan, W. Xu, D. Q. Xu, W. D. Xie, Y. Zhang,H.X.Xu*, N. H. Xu, The naturalcompound oblongifolin C inhibits autophagic fluxand enhances antitumor efficacy of nutrient deprivation,Autophagy, 10(5): 1-14 (2014). (IF=11.753)
2. G. Wan, W. D. Xie, Z. Y. Liu, W. Xu, Y. Z. Lao, N. Huang, K. Cui, M. J. Liao, J. He, Y. Y. Jiang, Burton B Yang,H. X. Xu, N. H. Xu, Y. Zhang,Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathway,Autophagy, 10(1): 70-79 (2014). (IF=11.753)
3. G. Lin, J. Y. Wang, N. Li, M. Li, H. Gao, Y. Ji, F. Zhang, H. L. Wang, Y. Zhou, Y. Ye,H. X. Xu, J. Zheng, Hepatics inusoidal obstruction syndrome associated with consumption ofGynura segetum,Journal of Hepatology, 54(4), 666-673(2011). (IF=11.336)
4. M.H.Feng, B.Q.Tang, N.Z.Wang,H.H.Xu, X.F.Jiang*, Ligand Controlled Regiodivergent C1 Insertion on Arynes for Construction of Phenanthridinone and Acridone Alkaloids,Angewandte Chemie (International ed. in English),doi:10.1002/anie.201508340. [Epub ahead of print] (2015). (IF=11.261)
5. H. L. Zhao, Y. Sui, C. F. Qiao, K. Y.Yip, R. K. K. Leung, S. K. W. Tsui, H. M. Lee, H. K. T. Wong, X. Zhu, J. J.Siu, L. He, J. Guan, L. Z. Liu,H. X.Xu, P. C. Y. Tong, J. C. N. Chan, Sustained antidiabetic effects of aberberine-containing Chinese herbal medicine through regulation of hepatic geneexpression,Diabetes, 61(4), 933-943(2012).(IF=8.095)
6. X. W. Yang,X. Deng,X. Liu, C. Y. Wu,X. N. Li,B. Wu, H. R. Luo, Y. Li,H. X. Xu, Q. S. Zhao, G. Xu, Hypercohin A,a new polycyclic polyprenylated acylphloroglucinols possessing an unusualbicyclo[5.3.1]hendecane core fromHypericum cohaerens,Chemical Communications, 48: 5998-6000 (2012). (IF=6.834)
7. Y. Liao, X. Liu,J. Yang, Y.Z. Lao, X.W.Yang, X.N.Li, J.J.Zhang, Z.J.Ding,H.X.Xu*and G. Xu*, Hypersubones A and B, New Polycyclic Acylphloroglucinols with Intriguing Adamantane Type Cores fromHypericum subsessile,Organic Letters, 17 (5), 1172–1175(2015). (IF=6.364)
8. Q. B. Han, T. F. Tso, S. Cheung, Tai, J.Z. Song, C. F. Qiao, H. D. Sun, andH.X. Xu*, Maoecrystal Z, a Cytotoxic Diterpene fromIsodon eriocalyxwith an Unique Skeleton,Organic Letters, 8 (21),4727-4730 (2006). (IF=6.364)
9. Z.J.Ding, Y.Z.Lao, H.Zhang, W.W.Fu, L.L.Zhu,H.S.Tan,H.X.Xu*, Griffipavixanthone, a dimeric xanthone extracted from edible plants, inhibits tumor metastasis and proliferation via downregulation of the RAF pathway in esophageal cancer,Oncotarget, in press.(2015).(IF=6.359)
10. X. H. Pang, J. Y. Song, Y. J. Zhu,H.X.Xu, L. F. Huang, S. L. Chen, Applying plant DNA barcodes for Rosaceae species identification,Cladistics, 27(2), 165-170 (2011). (IF=6.217)
11. K.K. Shen, J.L.Xie, H. Wang, H.Zhang, M.Y.Yu,F.F. Lu, H.S. Tan,H.X.Xu*,Cambogin induces caspase-independent apoptosis through the ROS/JNK pathway and epigenetic regulation in breast cancer cells,Molecular Cancer Therapeutics, 14(7):1738-1749. (2015). (IF=5.683)
12. T. W. D. Chan,P. P. H. But, S. W. Cheng, I. M. Y. Kwok, F. W. Lau,H. X. Xu, Differentiation and authentication ofPanax ginseng,Panax quinquefoliusand ginseng products by using HPLC/MS,Analytical Chemistry, 72(6), 1281-1287(2000). (IF=5.636)
13. X.Y. Wang, Y. Z. Lao, N.H. Xu, Z.C. Xu,M. Wu, H. Wang, X. Li, H.S. Tan, M.H. Sun,H.X. Xu*, Oblongifolin C inhibits metastesis by up-regulating keratin 18and tubulins,Scientific Reports,5:10293-10305.(2015). (IF=5.578)
14. W. L. Ting Kan, C. Yin,H. X. Xu*, G. Xu, K. K. W. To, C. H. Cho, J. A. Rudd, G. Lin, Antitumor effects of novel compound, guttiferone K, on colon cancer by p21Waf1/Cip1-mediatedG0/G1 cell cycle arrest and apoptosis,InternationalJournalofCancer, 132(3): 707-716(2013). (IF=5.085)
15. C. Feng, L. Y. Zhou, T. Yu, G. Xu, H. L. Tian, J. J. Xu,H.X.Xu*, K. Q. Luo, A new anticancer compound, Oblongifolin C, inhibits tumor growth and promotes apoptosis in HeLa cells through bax activation,InternationalJournalofCancer, 131(6): 1445-1454 (2012). (IF=5.085)
16. Z.C.Xi, M.Yao, Y.Li, C.L.Xie, J. Holst, T.Liu, S.F.Cai, Y.Z.Lao, H.S.Tan,H.X.Xu*and Q.H. Dong*,Guttiferone Kimpedes cell cycle re-entry of quiescent prostate cancer cellsviastabilization of FBXW7 and subsequent c-MYC degradation,Cell Death & Disease,under revised. (2015). (IF=5.014)
17. Y.Lu, S.F.Cai,J.Nie, Y.Y. Li, G.C.Shi, J.M.Hao, W.W.Fu, H.S.Tan, S.L.Chen, B. Li*,H.X.Xu*,The natural compound nujiangexanthone A suppresses mast cell activation and allergic asthma,Biochemical Pharmacology,S0006-2952(15)00713-3. doi: 10.1016/j.bcp.2015.11.004. [Epub ahead of print] .(2015). (IF=5.009)
18. D.H.He,L.S.Ding,H.X.Xu*,X.X.Lei,H.P.Xiao,Y.Zhou,GymnothelignansA-O:Conformation and Absolute Configuration Analyses of Lignans Bearing Tetrahydrofuran fromGymnotheca chinensis,Journal of Organic Chemistry,77(19): 8435-8443 (2012). (IF=4.721)
19. H. Y. Qin, J.C. Y. Wu, X. D. Tong, J. J. Y. Sung,H. X. Xu, Z. X.Bian, Systematic review of animal models ofpost-infectious/post-inflammatory irritable bowel syndrome.Journal ofGastroenterology, 46(2), 164-174 (2011). (IF=4.523)
20. Z. X. Bian, Z.Li, Z. X. Huang, M. Zhang, H. L. Chen,H.X. Xu, J. J. Y. Sung, Unbalanced expression of protease-activated receptors-1 and -2 inthe colon of diarrhea-predominant irritable bowel syndrome patients,Journal of Gastroenterology, 44(7),666-674 (2009). (IF=4.523)
21. Y. Zhou, N. Li,F. F. K. Choi, C. F. Qiao, J. Z. Song, S. L. Li, X. Liu, Z. W. Cai, P. P. Fu,G. Lin*,H. X. Xu*, A new approachfor simultaneous screening and quantification of toxic pyrrolizidine alkaloidsin some potential pyrrolizidine alkaloid-containing plants by using ultraperformance liquid chromatography-tandem quadrupole mass spectrometry,Analytica Chimica Acta, 681(1-2), 33-40 (2010). (IF=4.513)
22. Y. Zhou,Stephanie Lee, Franky F. K. Choi, G. Xu, X. Liu, J. Z. Song, S. L. Li, C. F.Qiao,H. X. Xu*, Qualitative and quantitative analysis of polycyclic polyprenylated acylphloroglucinols from Garcinia species using ultraperformance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry,Analytica Chimica Acta, 678(1), 96-107 (2010). (IF=4.513)
23. Y. Zhou, X. Liu,J. Yang, Q. B. Han, J. Z. Song, S. L. Li, L. S. Ding,H. X. Xu*,Analysis of caged xanthones from the resin ofGarcinia hanburyiusing ultraperformance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry,Analytica Chimica Acta,629, 104-118 (2008). (IF=4.513)
24. L. Z. Liu, S. C.K. Cheung, L. L. Lan, S. K. S. Ho,H.X. Xu, J. C. N. Chan, P. C. Y. Tong, Berberine modulates insulin signaling transduction in insulin-resistant cells,Molecular and Cellular Endocrinology, 317 (1-2), 148-153 (2010). (IF=4.405)
25. M.S. Liu, L.Tao, S. L. Chow, R. Wu, H.Zhang, Y.F.Yang, D.J.Yang, Z.X.Bian, A.P.Lu, Q.B.Han,H.H.Xu*,Folding fan mode counter-current chromatography offers fast blindscreening for drug discovery. Case study: finding anti-enterovirus 71 agents fromAnemarrhena asphodeloides.,Journal of Chromatography A, 1368：116-124 (2014). (IF=4.169)
26. S. L. Li, H. Shen, L. Y. Zhu, J. Xu, X. B. Jia, H. M. Zhang ,H.X.Xu*, G. Lin, H. Cai, B. C. Cai, S. L. Chen, Ultra-high-performance liquid chromatography-quadrupole/time of flight mass spectrometry based chemical profiling approach to rapidly reveal chemical transformation of sulfur-fumigated medicinal herbs, a case study on white ginseng,Journal of Chromatography A, 1231: 31-45 (2012).(IF=4.169)
27. Y. Zhou, J. Z. Song, Franky F. K. Choi, H. F. Wu, C. F. Qiao, L. S. Ding,S. L. Gesang,H. X. Xu*, An experimental design approach using response surface techniques to obtain optimal liquid chromatography and mass spectrometry conditions todetermine the alkaloids in Meconopsi species,Journal of Chromatography A, 1216 (42),7013-7023 (2009). (IF=4.169)
28. J. Z. Song, C. F. Qiao, S. L. Li, Y. Zhou, M.T. Hsieh,H. X. Xu*, Rapid optimization of dual-modegradient high performance liquid chromatographic separation of Radix etRhizoma Salviae Miltiorrhizaeby Response Surface Methodology,Journal of Chromatography A, 1216 (42), 7007-7012 (2009). (IF=4.169)
29. Y. Zhou, G. Xu,F. F. K. Choi, L. S. Ding, Q. B. Han, J. Z. Song, C. F. Qiao, Q. S. Zhao,H. X. Xu*, Qualitative and quantitative analysis of diterpenoidsin Salvia species by liquid chromatography coupled with electrospray ionizationquadrupole time-of-flight tandem mass spectrometry,Journal of Chromatography A, 1216(24), 4847-4858 (2009). (IF=4.169)
30. C. Y. Li,H. X. Xu, Q. B. Han, T. S. Wu,Quality assessmentRadix Codonopsisby quantitative nuclear magnetic resonance,Journal of Chromatography A,1216(11), 2124-2129 (2009).(IF=4.169)
31. Y. Zhou, Q. B.Han, J. Z. Song,H. X. Xu*, Characterization of polyprenylated xanthones inGarcinia xipshuanbannaensisusing liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry,Journal of Chromatography A, 1206 (2), 131-139 (2008). (IF=4.169)
32. Q. B. Han, J. Z.Song, C. F. Qiao, L. Wong, andH. X.Xu*, Preparative separationof gambogic acid and its C-2 epimer using recycling high-speed counter-current chromatography,Journal of Chromatography A, 1127(1-2), 298-301 (2006). (IF=4.169)
33. S. B. Chen, H.P. Liu, R. T. Yian, D. J. Yang, S. L. Chen,H. X. Xu, A. S. C. Chan, and P. S. Xie, High-performance thin-layer chromatographic fingerprints of isoflavonoids for distinguishing between Radix Puerariae Lobate and Radix Puerariae Thomsonii.Journal of ChromatographyA, 1121(1), 114-119 (2006). (IF=4.169)
34. Y. Xie, Z. H.Jiang, H. Zhou,H. X. Xu, andL. Liu, Simultaneous determination of six Aconitum alkaloids in proprietary Chinese medicines by high-performance liquid chromatography,Journal of ChromatographyA, 1093 (1-2), 195-203 (2005). (IF=4.169)
35. J. Z. Song,H. X. Xu, S. J. Tian, and P. P.H. But, Determination of quinolizidine alkaloids in traditional Chinese herbaldrugs by nonaqueous capillary electrophoresis,Journal of ChromatographyA,857, 303-311(1999). (IF=4.169)
36. X. J. Zhang, Z.Li, W. M. Leung, L. Liu,H. X. Xu,Z. X. Bian, The Analgesic Effect of Paeoniflorin on Neonatal Maternal Separation-Induced Visceral Hyperalgesia in Rats,Journal of Pain, 9 (6), 497-505 (2008). (IF=4.01)
37. X. J. Zhang, F. F. K. Choi, Y. Zhou, F. P. Leung, S. Tan, S. H. Lin,H. X. Xu, W. Jia, J. J. Y. Sung, Z. W. Cai, Z. X. Bian, Metabolite profiling of plasma and urine from rats withTNBS-induced acute colitis using UPLC-ESI-QTOF-MS-based metabonomics: A pilot study,FEBS Journal, 279(13): 2322-2338 (2012). (IF=4.001)
38. Y. W. Zhang, P.P. H. But, V. E. C. Ooi,H. X. Xu,G. D. Delaney, S. H. S. Lee, S. F. Lee, Chemical properties, mode ofaction, andin vivoanti-herpes activities of a lignin–carbohydrate complex fromPrunella vulgaris,Antiviral Research,75 (3),242-249 (2007). (IF=3.938)
39.H. X. Xu, S. H. S. Lee,S. F. Lee, R. L. White, J. Blay, Isolation and characterization of an anti-HSV polysaccharide fromPrunella vulgaris,Antiviral Research, 44(1), 43-54 (1999). (IF=3.938)
40. Kurokawa, H.Ochiai, K. Nagasaka,H. X. Xu,S. Kadota, T. Namba, and K. Shiraki, Antiviral traditional medicines against herpes simplex virus, poliovirus, and measles virus in vitro and their therapeutic efficacies for HSV infection in mice,Antiviral Research, 22, 175-188 (1993). (IF=3.938)
41. W. M. Fu, J. F. Zhang, H. Wang, Z.C. Xi, W.M. Wang, P. Zhuang, X. Zhu, S.C. Chen, T. M. Chan, K. S. Leung, G. Lu,H. X. Xu*, H. F. Kung, Heat shock protein 27 mediates the effect of 1,3,5-trihydroxy-13,13-dimethyl-2H-pyran [7,6-b] xanthone on mitochondrial apoptosis in hepatocellular carcinoma,Journal of Proteomics, 75(15): 4833-4843 (2012). (IF=3.888)
42. Q. B. Han,H. X. Xu*, Caged Garcinia Xanthones: Development Since 1937,Current Medicinal Chemistry, 16 (28), 3775-3796 (2009).Review(IF=3.853)
43. W.W.Fu, M.Wu, L.L.Zhu, Y.Z. Lao,L.P.Wang, H.S.Tan, Q.H. Yuan,H.X.Xu*. Prenylated benzoylphloroglucinols and biphenyl derivatives from the leaves ofGarcinia multifloraChamp,RSC Advances,5, 78259-78267 (2015). (IF=3.84)
44. Y.J.Wang, H.Zhang, Q.Z. Zhang, Y.J. Liang, L.Ma, H.S.Tan, Y.Z.Lao*,H.X. Xu*and Z.G.Li*,Genetically encoded fluorescence screening probe for MgrA, a global regulator in Staphylococcus aureus,RSC Advances,5, 87216-87220 (2015). (IF=3.84)
45. G.Y.He, S.X.Zhang, L.Xu, Y.L.Xia,P.Wang, S.Y.Li, L.L.Zhu, H.X.Xu, G.B.Ge andL.Yang, C-8 Mannich base derivatives of baicalein display improved glucuronidation stability: exploring the mechanism by experimentation and theoretical calculations,RSC Advances,DOI: 10.1039/C5RA20213B (2015).(IF=3.84) 2015-10-14
46. X. Wang, Y. C.Chen, Q. B. Han, C. Y. Chan, H. Wang, Z. Liu, C. H. K. Cheng, D. T. Yew, M. C.M. Lin, M. L. He,H. X. Xu*,J. J. Y. Sung, H. F. Kung, Proteomic identification of molecular targets of gambogic acid: Role of stathmin in hepatocellular carcinoma,Proteomics, 9(2), 242-253 (2009). (IF=3.807)
47. H. Zhang, D. D. Zhang, Y. Z. Lao, W. W.Fu, S. Liang, Q. H. Yuan, L. Yang, andH.X.Xu*,Cytotoxic and Anti-inflammatory Prenylated Benzoylphloroglucinols and Xanthones from the Twigs ofGarcinia esculenta,Journal of Natural Products, 77:1700-1707(2014). (IF=3.798)
48. H. Zhang, L.Tao, W. W. Fu, S. Liang, Y. F. Yang, Q. H. Yuan, D. J. Yang, A. P. Lu,H.X.Xu*,Prenylated benzoylphloroglucinolsand xanthones from the leaves ofGarcinia oblongifoliawith antienteroviral activity,Journal of Natural Products, 77:1037-1046(2014). (IF=3.798)
49. C. Feng, S. X. Huang, X. M. Gao,H.X.Xu*, Kathy Luo, Characterization of proapoptotic compounds from the bard ofGarcinia oblongifolia,Journal of Natural Products. 77:1111-1116 (2014). (IF=3.798)
50. Z. X. Xia, D. D. Zhang, S. Liang, Y. Z. Lao, H. Zhang, H. S. Tan, S. L. Chen, X. H. Wang,H.X.Xu*. Bioassay-Guided Isolation of Prenylated Xanthones and Polycyclic Acylphloroglucinols from the Leaves ofGarcinia nujiangensis，Journal of Natural Products. 75(8): 1459-1464 (2012). (IF=3.798)
51. X. Liu, T. Yu,X. M. Gao, Y. Zhou, C. F. Qiao, Y. Peng, S. L. Chen, Kathy Q. Luo,H. X. Xu*, Apoptosis effects of Polyprenylated Benzoylphloroglucinol Derivatives from the Twigs ofGarcinia multiflora,Journal of Natural Product, 73(8),1355-1359 (2010).(IF=3.798)
52. G. Xu, W. L. T.Kan, Y. Zhou, J. Z. Song, Q. B. Han, C. F. Qiao, C. H. Cho, J. A. Rudd, G. Lin,H. X. Xu*, Cytotoxic acylphloroglucinol derivatives from the twigs ofGarcinia cowa,Journal of Natural Product, 73(2), 104-108 (2010).(IF=3.798)
53. S. X. Huang, C.Feng, Y. Zhou, G. Xu, Q. B. Han, C. F. Qiao, D. C. Chang, K. Q. Luo,H. X. Xu*, Bioassay-guided isolation of xanthones and polycyclic prenylated acylphloroglucinols fromGarcinia oblongifolia,Journal of Natural Product, 72 (1),130-135 (2009). (IF=3.798)
54. R. W. Jiang, J.R. Zhou, P. M. Hon, S. L. Li, Y. Zhou, L. L. I, W. C. Ye,H. X. Xu,P. C. Shaw, P. P. But, Lignans from Dysosma versipellis with Inhibitory Effects on Prostate Cancer Cell Lines,Journal of Natural Product, 70 (2), 283-286 (2007).(IF=3.798)
55. R. W. Jiang, P. M. Hon, Y. Zhou, Y. M. Chan, Y. T. Xu,H. X. Xu,H. Greger, P. C. Shaw, P. P. H. But, Alkaloids and Chemical Diversity ofStemona tuberose,Journal of Natural Product, 69(5), 749-754 (2006). (IF=3.798)
56. H. Dong, S. X. Chen, R. M. Kini,H. X. Xu, Effects of Tannins fromGeum japonicumon the Catalytic Activity of Thrombin and Factor Xa of Blood Coagulation Cascade,Journal of Natural Product, 61(11),1356-1360 (1998). (IF=3.798)
57. H. Dong, S. X.Chen,H. X. Xu, S, Kadota,and T. Namba, A new antiplatelet Diarylheptanoid fromAlpinia blepharocalyx,Journal of Natural Product, 61 (1), 142-144 (1998).(IF=3.798)
58.H. X. Xu, F. Q. Zeng, M.Wan, K. Y. Sim,Anti-HIV triterpene acids fromGeum japonicum,Journal of Natural Product, 59 (7), 643-645 (1996).(IF=3.798)
59. L. T. Yi, Y.C.Li, Y. Pan, J. M. Li, Q. Xu, S. F. Mo, C. F. Mo, F. X. Xu,H. X. Xu,X. B. Lu, L. D. Kong, H. F. Kung,Antidepressant-like effects of psoralidin isolated from the seeds ofPsoralea Corylifoliain the forced swimming test in mice,Progress in Neuro-Psychopharmacology & Biological Psychiatry, 15; 32(2), 510-519 (2008). (IF=3.689)
60. W.M. Fu, L.P. Tang, X. Zhu, Y.F. Lu,Y.L. Zhang, W.Y. Lee, H. Wang, Y. Yu, W.C. Liang, C.H. Ko,H.X.Xu,H.F. Kung, J.F. Zhang.MiR-218-targeting-Bmi-1mediates the suppressive effect of 1,6,7-trihydroxyxanthone on liver cancercells,Apoptosis,20(1):75-82. (2015). (IF=3.685)
61. W. M. Fu, J.F. Zhang, H. Wang, H. S. Tan, W. M. Wang, S. C. Chen, X. Zhu, T. M. Chan, C. M.Tse, K. S. Leung, G. Lu,H. X. Xu*, H. F. Kung, Apoptosis induced by 1,3,6,7-tetrahydroxyxanthone in Hepatocellular carcinoma and proteomic analysis,Apoptosis, 17(8): 842-851 (2012). (IF=3.685)
62. Q. B. Han, T.Yu, F. Lai, Y. Zhou, C. Feng, W. N. Wang, X. H. Fu, C. B. S. Lau, K. Q. Luo,H. X. Xu, H. D. Sun, K. P. Fung,P. C. Leung, Quick identification of apoptosis inducer from Isodon eriocalyx bya drug discovery platform composed of analytical high-speed counter-current chromatography and the fluorescence-based caspase-3 biosensor detection,Talanta, 82(4), 1521-1527 (2010). (IF=3.545)
63. Q. B. Han, Y. K.Yip, N. Y. Yang, L. Wong, C. F. Qiao, J. Z. Song, H. Yiu,H. X. Xu*, Rapid analysis of pseudolaric acids inCortex Pseudolaricisand related medicinal products by high performance liquid chromatography,Talanta, 73(4), 757-763 (2007). (IF=3.545)
64. S. D. Qi, S. L.Tian,H. X. Xu, J. J. Y.Sung, Z. X. Bian, Quantification of luminally released serotonin in rat proximal colon by capillary electrophoresis with laser-induced fluorescencedetection,Analytical and Bioanalytical Chemistry, 393 (8), 2059-2066 (2009). (IF=3.436)
65. H. S. Tan, D. D. Hu, J. Z. Song, Y. Xu, S. F. Cai, Q. L. Chen, Q. W. Meng, S. L. Li, S. L. Chen, Q. Mao,H. X. Xu*, Distinguishing Radix Angelica sinensis from different regions by HS-SFME/GC-MS,Food chemistry,186:200-206 (2015)(IF=3.391)
66. B. Xia, Y. Zhou, H. S. Tan, L. S. Ding,H.X.Xu*,Advanced ultra-performance liquid chromatography-photodiodearray-quadrupole time-of-flight mass spectrometric methods for simultaneous screening and quantification of triterpenoids inPoria cocos,Food Chemistry, 152: 237-244 (2014). (IF=3.391)
67. X.Li, Y.Z.Lao, H.Zhang, X.Y.Wang,H.S.Tan, Z.X.Lin,H.X.Xu*,The natural compound Guttiferone F sensitizes prostate cancer to starvation induced apoptosis via calcium and JNK elevation,BMC Cancer,15:254-266,(2015).(IF=3.362)
68. X. Wang, Y.J. Lou, M. X. Wang, Y. W. Shi,H. X.Xu*, L. D. Kong, Furocoumarins affect hepatic cytochrome P450 and renal organic ion transporters in mice,Toxicology Letters, 209(1): 67-77 (2012). (IF=3.262)
69. Ruby L. C. Hoo,Janice Y. L. Wong, C. F. Qiao, A. Xu,H.X. Xu*, Karen S. L. Lam, The effective fraction isolated from Radix Astragali alleviates glucose intolerance, insulin resistance and hypertriglyceridemia in db/db diabetic mice through its anti-inflammatory activity,Nutrition & Metabolism,7, 67 (2010). (IF=3.258)
70. D.D.Zhang, H.Zhang, Y.Z.Lao, R.Wu,J.W.Xu, F.Murad, K. Bian,H.X.Xu*,Anti-Inflammatory Effect of 1,3,5,7-Tetrahydroxy-8-isoprenylxanthone Isolatedfrom Twigs of Garcinia esculenta on Stimulated Macrophage,Mediators of Inflammation, http://dx.doi.org/10.1155/2015/350564(2015). (IF=3.236)
71. H. Yao, J. Y.Song, C. Liu, K. Luo, J. P. Han, Y. Li, X. H. Pang,H. X. Xu, Y. G. Zhu, P. G. Xiao, S. L. Chen, Use of ITS2 Region as the Universal DNA Barcode for Plants and Animals,PLoS One, 5(10), e13102 (2010). (IF=3.234)
72. X.Y.Wang, L.F.Xu, Y.Z.Lao, H.M.Zhang,andH.X.Xu*, Natural productstargeting EGFR signaling pathways as potential anticancer drugs,Current Protein & Peptide Science,under revised(IF=3.154)
73. M.Wu, Y.Z.Lao, N.H.Xu, X.Y.Wang,H.S.Tan,W.W.Fu, Z.X.Lin,H.X.Xu*.Guttiferone K induces autophagy and sensitizes cancer cells to nutrientstress-induced cell death，Phytomedicine，22(10), 902-910(2015). (IF=3.126)
74. M. Zhang, K. H. Zang, J. L. Luo, F. P. Leung, Y. Huang, C. Y. Lin, Z. J. Yang, A. P. Lu, X. D. Tang,H.X.Xu, Joseph J. Sung, Z. X. Bian, Magnolol inhibits colonic motility through down-regulation of voltage-sensitive L-type Ca2+ channels of colonic smooth muscle cells in rats,Phytomedicine, 20（14）:1272-1279 (2013). (IF=3.126)
75. Y. F. Wong, H.Zhou, J. R. Wang, Y. Xie,H. X. Xu,L. Liu, Anti-inflammatory and analgesic effects and molecular mechanisms of JCICM-6, a purified extract derived from an anti-arthritic Chinese herbalformula.Phytomedicine, 15, 416-426(2008). (IF=3.126)
76. M.S. Liu, S.L.Chau,D.L. Ma, C.H. Leung, Z.X.Bian, A. P.Lu,H.X.Xu*, Q.B. Han*, Using two-phase solvent systems for sample pretreatment increases yield of counter-current chromatography:Anemarrhena asphodeloides saponins, a case study,Separation and PurificationTechnology, 138:138-143, (2014). (IF=3.091) 。